CRISPR can edit whole chromosomes! by Meredith Jacques

CRISPR can edit whole chromosomes! by Meredith Jacques

image source: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/karyotyping

CRISPR is a gene editing system that was discovered not long ago which has been able to speed up the process of genetic engineering.  What used to be a process that would take a series of reactions over the course of days, even weeks, can now be done in a much shorter amount of time.  CRISPR targets a gene and can replace it with a new piece of DNA, all in one step.  Last year, a scientist edited a human embryo with CRISPER technology.  A new study shows that CRISPR can actually work on much larger chunks of DNA at a time and edit at the chromosome level.


What could this mean for the future of medicine?
What ethical considerations do we have to consider with this kind of technology?
What kinds of problems could this kind of technology solve or create?

https://www.sciencemag.org/news/2019/08/forget-single-genes-crispr-now-cuts-and-splices-whole-chromosomes
original research: https://science.sciencemag.org/content/365/6456/922
more research: https://www.ncbi.nlm.nih.gov/pubmed/28633863
CRISPR editing of embryos: https://www.newscientist.com/article/2186732-crispr-scientist-says-another-woman-is-pregnant-with-an-edited-embryo/

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